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Mercedes-Benz S-Class W221 (2005-2013) – fuse box

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Mercedes-Benz S-Class w221 (2005-2013) – fuse box diagram

Year of production: 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013.

The cigarette lighter fuse (power socket) on the Mercedes S-Class w221 (2005-2013)  is fuse 43 in the fuse box in the engine compartment

Fuse box in the engine compartment

Mercedes-Benz S-Class W221 – fuse box diagram – engine compartment
Number Description Amperes [A]
20 Valid for engines 629, 642, 651:

CDI control unit;

Valid for engines 156, 157, 272, 273, 275, 276, 278:

ME-SFI [ME] control unit.

 10
21 Valid for engines 156, 157, 272, 273, 275, 276, 278:

Terminal 87 of M1 connector sleeve i;

Valid for model 221 with engine 629 and engine 642:

CDI control unit;

Fuel pump relay;

Valid for model 221 with engine 651:

Valve quantity control.

 20
22 Valid for engines 156, 157, 272, 273, 276, 278:

Terminal connector sleeve 87.

 15
23 up to 2008:
Terminal 87 connector bush;
Valid for engine 275 (model 216):
Terminal 87 M1 i connector bush;
Valid for engine 273 (model 216):
Terminal 87 M2e connector bush;
Valid for engine 272, 273 (model 221):
Compression fitting 87M2i Sleeve;
Valid for engine 642:
Terminal 87 connector bush;
as of 2009:
Valid for engine 156, 157, 272, 273, 275, 276, 278:
Terminal 87 connector bush;
For model 221 with engine 629 and engine 642:
Terminal 87 connector bush;
Valid for engine 156, 157, 272, 273, 276, 278:
terminal 87M2e terminal connector sleeve;
Valid for engine 275:
Terminal 87 M2i connector sleeve;
Valid for model 221 with engine 629 and engine 642:
Terminal 87 connector bush;
For model 221 with engine 651:
Rear SAM control unit with fuse and relay module.		 20
24 Valid for engines 157, 272, 273, 276, 278:

Terminal connector sleeve 87M1e D;

Valid for engine 642:

CDI control unit.

 25
25 Instrument cluster 7.5
26 Left Headlight Assembly 10
27 Right headlight assembly 10
28 Valid for engine 275:
EGS control unit;
Valid without engine 275:
Fully integrated transmission control unit (VGS).		 7.5
29 Rear SAM control unit with fuse and relay module 5
30 Valid for engines 629, 642, 651:

CDI control unit;

Valid for engines 156, 157, 272, 273, 275, 276, 278:

ME-SFI [ME] control unit;

Fuel pump control unit.

 7.5
31 S400 Hybrid:  

electric refrigerant compressor.

 5
32 For model with ECO start / stop function:

Additional gear oil pump controller;

S 400 Hybrid:

Additional gear oil pump controller.

 15
33 Valid from 1.9.10 without S 400 Hybrid:

ESP control unit;

S 400 Hybrid:

Battery management system control unit;

DC / DC converter control unit;

Power electronics control unit.

 5
34 S 400 Hybrid:

Braking system control unit with energy recovery

 5
35 Electric parking brake control unit  5
36 Data link connector (pin 16) 10
37 To the EIS control unit  7.5
38 Central gate control unit 7.5
39 Instrument cluster  7.5
40 Top control panel control unit 7.5
41 Wiper sub motor  30
42 Main wiper motor  30
43 Front cigarette lighter with ashtray illumination 15
44 – –
45 S 400 Hybrid: Electronic circulation pump 1 5
46 W221 with Active Body Control (ABC) model 216:  

ABC;

W221 without Active Body Contro (ABC):  

AIRmatic with ADS.

 15
47 Front SAM control unit with fuse and relay module;

Steering column lifting and lowering motor.

 15
48 up to 2008:  

Front SAM control unit with fuse and relay module;

since 2009:  

Steering column lifting and lowering motor.

 15
49 Steering column module  10
50 AAC [KLA] control unit 15
51 up to 2008: 

COMAND display 

 7.5
since 2009:

COMAND display;

SPLITVIEW display.

 5
52 A. W221:

Left horn;

Right horn.

 15
52 B W221, C216:

Left horn;

Right horn.

 15
53 – –
54 AC air recirculation unit 40
55 Valid for gasoline engine:

Electric air pump

 60
56 W221 without Active Body Contro (ABC):

AIRmatic compressor

 40
57 up to 2008:

Wiper parking heater

 40
from 2009:

Wiper parking heater

 30
60 from 2009:

Electro-hydraulic power steering

 5
61 C216; W221 – from 2009:

Restraint systems control unit

 7.5
W221; up to 2008:

Restraint systems control unit

 10
62 Night View Assist control unit 5
63 Valid for model 221 with engine 629 and engine 642 as of 1.9.08:

Fuel filter condensation sensor with heating element

 15
64 W221 as of 1.9.06:

NECK-PRO driver’s headrest electromagnet;

Passenger’s headrest solenoid NECK-PRO.

 7.5
W221 from ’09:

NECK-PRO driver’s headrest electromagnet;

Passenger’s headrest solenoid NECK-PRO.

 10
65 Valid from 1.6.09:

12V connector in glove box

 15
66 DTR control unit (Distronic or Distronic Plus) 7.5
Relay
A Air pump relay
B Air suspension compressor relay
C. Relay 87, engine
D Terminal 15 relay
E. Terminal 87 relay, chassis
F. Horn relay
G. Terminal 15R relay
H. Circuit 50 of relay, starter
J. Circuit 15 of relay, starter
K. Wiper parking heater relay

Left dashboard fuse box

Mercedes-Benz S w221 – fuse box diagram – left instrument panel
Number Description Amperes [A]
92 Left front seat control unit 40
93 Restraint systems control unit;

USA version:

Mass detection system (WSS) control unit.

 7.5
94 since 2009:

Multifunctional camera.

 5
95 – –
96 Tire pressure monitor control unit [RDK] 5
97 W221:

Audio / video controller control unit (rear entertainment system).

 7.5
98 Rear entertainment system:

DVD player (from 2009)

 7.5
99 since 2009:

COMAND display;

SPLITVIEW display.

 7.5
100 since 2009:

Multimedia interface control unit

 5
101 Rear entertainment system:

Left rear display;

Right rear display.

 10
102 Right front seat control unit 40
103 ESP control unit 7.5
104 Audio tuner control unit 40
105 – –
106 Japanese version:

Electronic toll collection (ETC) control unit;

Valid for South Korea as of 1.9.10:

TV / tuner connector;

It concerns navigation; since 2009:

Navigation processor.

 1
107 SDAR (SIRIUS satellite radio) control unit (W221 from 2009);

Radio;

Digital Audio Broadcasting control unit;

Radio HD:

High definition tuner control unit.

 5
108 W221:

Rear air conditioning control unit

 5
109 W221:

Rear blower adapter

 15
110 W221:

Multicontour left rear seatback control;

Multicontour right rear seatback control.

 7.5
111 Rear multicontour seat or rear entertainment system (Model 221):

RCP [HBF] control unit

 5
112 W221; up to 2008:

Left front door control unit;

Right front door control unit;

S 400 Hybrid:  

Front SAM control module with fuse and relay module.

 5
113 S 400 Hybrid: 

DC / DC converter control unit

 5

Right-hand instrument panel fuse box

Mercedes-Benz S w221 – fuse box diagram – right instrument panel
Number Description Amperes [A]
70 C216:

Right door control unit;

W221:

Right front door control unit.

 40
71 Keyless Go control unit 15
72 S 400 Hybrid:  

Pyrotechnic separator

 7.5
73 Japanese version:

COMAND driver;

TELE AID emergency call system (from 2009):

Emergency call system control unit.

 5
74 TLC [HDS] control unit (remote trunk closing) 30
75 S 400 Hybrid:

Battery management system control unit;

Power electronics control unit.

 10
76 S 400 Hybrid:

Vacuum pump relay (+)

 15
Valid for model 221 with engine 642.8:

AdBlue® relay feed  .

 –
77 Advanced sound system:

Sound amplifier (from 2009).

 50
78 S 65 AMG with 275 engine:

Fan relay (from 2009);

Valid for 221 with engine 642.8:

AdBlue  ®  supply relay (from 2009).

 25
S 400 Hybrid, CL 63 AMG with engine 157, 278:

Charge air cooler circulation pump (from 2009).

 15
79 Alarm signaling device with additional battery 7.5
80 C216:

Left door control unit;

W221:

Left front door control unit.

 40
81 C216:

Rear control unit

 30
W221:

Left rear door control unit

 40
82 C216:

Rear control unit

 30
W221:

Left rear door control unit

 40
83 Intelligent servo module for DIRECT SELECT 40
84 Advanced sound system:

Digital sound processor (from 2009)

 20
85 Valid for AMG:

Illuminated door sills (from 2009)

 10
86 – –
87 – –
88 – –
89 – –
90 Stationary heater:

STH heater (model 216);

STH or HB heater (model 221).

 20
91 Stationary heater:

Radio remote control receiver STH;

S 400 Hybrid:

Front SAM control unit with fuse and relay module.

 5

Rear fuse and relay box

Mercedes-Benz S w221 – fuse box diagram – rear compartment
Number Description Amperes [A]
115 Heated rear window 50
116 Valid for engines 157, 275, 278:

Charge air cooler circulation pump;

Valid for engine 156:

Engine coolant circulation pump;

S 400 Hybrid:  

Power electronics circulation pump 2.

 10
117 Rear cigar lighter 15
118 Valid for engine 272, 273, 642:

Fuel pump (up to 2008);

Valid for model 221 with engine 629, 642:

Fuel pump (from 2009).

 30
S 400 Hybrid:

Power electronics circulation pump 1;

Valid for model 642.8 and engine 651 as of 1.6.11:

The compressor  refrigerant  refrigerant  with a magnet.

 15
119 Central control unit at the front 7.5
120 – –
121 Audio tuner control unit 10
122 COMAND control unit 7.5
123 W221:

Right front reversible emergency tensioner

 40
124 W221:

Front left reversible emergency tensioner

 40
125 to 31.5.09:

Voice control system (VCS) control unit

 5
126 Suspended control panel control unit 25
127 Lumbar pump (from 2009);

Multicontour Seat Air Pump (Left / Right front multicontour seat);

Pneumatic pump for dynamic seat control (Left and right dynamic multi-contour seat).

 30
128 Valid for engine 275 (up to 2008):

Fuel pump control unit;

Valid for engine 156, 157, 272, 273, 275, 276, 278, 642 (from 2009):

Fuel pump control unit.

 25
129 up to 2008:

The control unit control panel (roof -przesuwny tilt
of the glass);since 2009:UPCI (Universal Portable Cell Phone Interface) control unit.

 25
130 Electric parking brake control unit 30
131 Rear window antenna amplifier module 7.5
133 Trailer recognition control unit;

Reversing camera (from 1.9.10).

 15
134 Trunk socket 15
135 Park Assist; up to 2008:

Radar sensors control unit (SGR);

Front short-range radar unit;

Rear short-range radar unit;

DISTRONIC PLUS up to 31.8.10 or Blind Spot Assist or Adaptive Cruise Control Plus Light:

Radar sensors control unit (SGR) (from 2009);

PARKTRONIC or Exclusive Parking Assistant:

PTS control unit.

 7.5
136 Valid for model 221 with engine 642.8:

AdBlue® control unit .

 7.5
137 Reversing camera (as of 1.9.10) 7.5
138 Navigation processor (from 2009) (up to 8/31/10);

Emergency call system control unit (from 2009);

Japanese version:

TV / tuner connector (from 2009).

 5
139 Rear seat refrigerator 15
140 Rear cigarette lighter with ashtray illumination connector;

115V socket (from 2009).

 15
141 Reversing camera control unit 5
142 Parktronic system control unit (PTS);

Distronic Plus:

Radar sensors control unit (SGR);

Valid from 1.9.10 for DISTRONIC PLUS and Active Blind Spot Assist or Active Lane Keeping Assist:

Video and radar sensor system control unit.

 7.5
143 Rear seat control unit 25
144 Rear seat control unit 25
145 Trailer recognition control unit (up to 2008);

Trailer hitch socket (13-pin) (from 2009).

 20
146 Trailer recognition control unit 25
147 up to 2008:

TLC [HDS] control unit (remote trunk closing)

 30
148 up to 2008:

Universal Portable CTEL Control Unit (UPCI [UHI])

 7.5
since 2009:

Panoramic sliding sunroof, circuit 30 connecting sleeve

 25
149 up to 2008:

Voice control system control unit (VCS [SBS])

 5
since 2009:

Panoramic sliding sunroof control module

 25
150 Combined TV tuner (analog / digital);

Japanese version:

TV / tuner connector (from 2009).

 7.5
151 W221; up to 2008:

Electric parking brake control unit

 25
W221; since 2009:

Trailer recognition control unit

 20
152 W221:

Rear window antenna amplifier module

 7.5
115 V socket:

DC / AC converter control unit

 25
Relay
M. Terminal 15 relay
N Terminal 15R relay
O Power socket relay
P. Heated rear window relay
Q Valid for engine 156, 157, 275, 278, 629:

Circulation pump relay

S 400 Hybrid:  

Valid for model 221.095 / 195:

Power electronics circulation pump relay 2
R Cigarette lighter relay
S Fuel pump relay
Valid for engine 642.8 and engine 651 as of 1.6.11:

Connected by the fuel pump:

Refrigerant compressor magnetic clutch;

S 400 Hybrid:  

Power electronics circulation pump relay 1.

Inner pre-box (up to 2008)

Mercedes-Benz S – W221 – Fuse box diagram – inside fuse box
Number Description Amperes [A]
1 Starter 400
2 Does not apply to engine 642:

Alternator

 150
Valid for engine 642:

Alternator

 200
3 – 150
4 AAC with integrated control of an additional fan motor 150
5 Valid for engine 642:

PTC heating amplifier

 200
6 Front SAM control unit with fuse and relay module 200
7 ESP control unit 40
8 ESP control unit 25
9 Front SAM control unit with fuse and relay module 20
10 Vehicle power control unit 7.5

Inner pre-box (from 2009)

Mercedes-Benz S – W221 – Fuse box diagram – inside fuse box
Number Description Amperes [A]
3 Rear SAM control unit with fuse and relay module 150
4 Feature the ECO start / stop:

ECO start / stop function relay ;

S 400 Hybrid:

Controller with DC / DC converter;

Heated windscreen:

Heated windscreen.

 150
5 Valid for model 221 (electrical system in the rental vehicle):

Special vehicle multifunction control unit (SVMCU [MSS]).

 40
S 400 Hybrid:

Vacuum pump

 80
6 Right dashboard fuse box 80
7 Valid for model 221 with engine 629, 642, 651:

PTC heater amplifier;

Valid for model 221
(Pre-  wiring for rental vehicle):

Special vehicle multifunction control unit (SVMCU [MSS]).

 150
8 Front SAM control unit with fuse and relay module 80
9 Left dashboard fuse box 80
10 Rear SAM control unit with fuse and relay module 150

Engine compartment pre-fuse box (up to 2008)

Mercedes-Benz S – w221 – fuse box diagram – engine compartment pre-fuse box
Number Description Amperes [A]
1 Front fuse box
(via pirofuse on-board electrical network)		 –
2 Heated windscreen control unit 125
3 Right-hand instrument panel fuse box 80
4 Rear SAM control unit with fuse and relay module 200
5 Special vehicle multifunction control unit (SVMCU [MSS]) 100
6 Rear SAM control unit with fuse and relay module 150
7 Front SAM control unit with fuse and relay module 100
8 Left dashboard fuse box 80
9 Front SAM control unit with fuse and relay module 5
10 C216:

Emergency call system control unit

 5

Engine compartment pre-fuse box (from 2009)

Mercedes-Benz S – w221 – fuse box diagram – engine compartment pre-fuse box
Number Description Amperes [A]
2 Alternator 460
3 Electro-hydraulic power steering;

Valid for model 221 with engine 629, 642:

Burn time output stage.

 150
4 Inner pre-box (not used) –
5 AAC with integrated control of an additional fan motor 100
6 Front SAM control unit with fuse and relay module 150
7 ESP S 400 Hybrid control unit:  

Braking system control unit with energy recovery.

 40
8 ESP control unit;

S 400 Hybrid:  

Braking system control unit with energy recovery.

 25
9 Front SAM control unit with fuse and relay module 25
10 Reserve –

AdBlue fuse block

Mercedes-Benz S – W221 – Fuse box diagram – AdBlue fuse block
Number Description Amperes [A]
A AdBlue® control unit 7.5
B Heating circuit 1 20
C. Heating circuit 1 20
D Reserve –

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